Additive Effect of Early Life Adversities and Polygenic Risk on Suicide Attempt in Schizophrenia
Vincenzo De Luca, Ph.D., CAMH Psychiatry (Canada)
2016 Pilot Research Grant
Inside the Research
Question: Do schizophrenia related genes interact with childhood trauma to modulate suicide risk?
Strategy: Examine history of childhood trauma and 108 genetic markers for schizophrenia in a sample of people with schizophrenia. Individuals with and without suicide attempts and childhood trauma will be compared.
Impact: Use of gene-environment interactions to identify suicide risk.