Creation of Human Induced Pluripotent Stem Cells (hiPSCs) From Postmortem Brain Tissue of Suicide Completers
Megan Fitzgerald, B.A., Ph.D., The Trustees of Columbia University in the City of New York
Mentor: Victoria Arango, Ph.D., The Trustees of Columbia University in the City of New York
2015 Young Investigator Grant
Inside the Research
Question: Can brain cells generated from people who died by suicide tell us about risk?
Strategy: Grow hiPSC neuronal colonies using postmortem brain tissue from nine matched pairs of suicides, and compare with colonies from a control group. Living neurons can be correlated with brain anatomy and clinical observations.
Impact: Brain biology of suicide can be actively studied.