MicroRNA Mediators of Early-Life Stress Vulnerability in Suicidal Behavior
Yogesh Dwivedi, Ph.D., University of Alabama at Birmingham
2019 Distinguished Investigator Grant
Early life stress has been shown to contribute to suicide risk, but the mechanisms are unknown. Genetics play a role in brain function, and alterations in expression of specific microRNAs — the parts of genes that are responsive to environmental cues — may have an effect. Understanding the relationship between microRNAs, stress, and suicide has implications for developing novel treatments and suicide prevention strategies.