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Additive Effect of Early Life Adversities and Polygenic Risk on Suicide Attempt in Schizophrenia

2016 Pilot Research Grant
Amount Awarded: $27,658
Focus Areas: Neurobiological Studies, Genetic Studies

Vincenzo De Luca, Ph.D.
CAMH Psychiatry (Canada)

Inside the Research

Question:  Do schizophrenia related genes interact with childhood trauma to modulate suicide risk?

Strategy: Examine history of childhood trauma and 108 genetic markers for schizophrenia in a sample of people with schizophrenia.  Individuals with and without suicide attempts and childhood trauma will be compared.

Impact: Use of gene-environment interactions to identify suicide risk.