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Epigenetic risk factors for suicide in comorbid depression and alcoholism

2020 Standard Research Grant
Amount Awarded: $100,000
Focus Area: Genetic Studies

Craig Stockmeier, Ph.D.
University of Mississippi Medical Center

Inside the Research

When an individual suffers from alcohol use disorder (AUD) and depressive disorder (DEP) at the same time, they experience a worse course of illness and higher risk for suicide than either disorder alone. Individuals who die by suicide with concurrent AUD plus DEP may also experience greater changes in their brain (orbitofrontal cortex) and this is what this study investigates. Understanding these changes may improve the treatment and prevention of suicide among those with AUD and DEP.