Research finding · October 2026
Screening plus skills-building may improve nurse wellbeing and reduce burnout and suicidal ideation
Burnout and mental health challenges among nurses can affect not only their own wellbeing, but also workforce retention, patient safety, and the quality of care they provide. Nurses experiencing distress may also hesitate to seek help because of stigma, confidentiality concerns, or fears about professional consequences. Confidential mental health screening can help identify people who may need care and connect them with resources, but identification is only the first step; screening must be paired with follow-up action to address distress and build skills for managing it over time. Researchers are therefore examining whether combining psychologically safe screening and referral with accessible, evidence-based interventions can improve nurses’ mental health, wellbeing, and suicide-related outcomes.
With her AFSP-funded grant, Dr. Bernadette Mazurek Melnyk and colleagues adapted MINDBODYSTRONG, a cognitive behavioral skills-building program developed by Dr. Melnyk, into an online video-based intervention. They then conducted the first randomized controlled trial to test whether adding a digital skills-building intervention to confidential screening and referral could improve outcomes for nurses experiencing mental distress. The study enrolled 501 nurses across the United States, who received either AFSP’s Interactive Screening Program (ISP) with referral or ISP combined with MINDBODYSTRONG, which teaches practical skills for managing thoughts, emotions, stress, sleep, problem-solving, and wellbeing.
Compared with screening and referral alone, nurses offered MINDBODYSTRONG showed greater improvements in anxiety, depression, and healthy lifestyle beliefs and behaviors over three and six months, as well as a significantly lower risk of burnout at six months. Suicidal ideation declined in both groups, but the decrease was particularly notable among nurses receiving MINDBODYSTRONG, falling from 13.7% at baseline to 2.8% at six months—an approximately 80% reduction—compared with a decline from 16.3% to 8.3% among those receiving screening and referral alone. The difference between groups, however, did not reach statistical significance. The findings suggest that pairing psychologically safe screening and referral with scalable skills-building can provide additional benefits for nurses experiencing mental distress, while both groups showed substantial reductions in suicidal ideation.
Citation: Melnyk, B. M., J. E. Davidson, S. Tucker, et al. 2026. “Effects of Digital Mental Health Screening Alone and With the Online MINDBODYSTRONG CBT-Based Program on Burnout, Depression, Anxiety, Healthy Behaviors, and Suicidal Ideation in at-Risk Nurses at 3- and 6-Months Post-Intervention: An RCT.” Worldviews on Evidence-Based Nursing 23, no. 5: e70171. https://doi.org/10.1111/wvn.70171
This finding comes from an AFSP-funded study — see the grant below ↓