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Inflammatory and Insulinemic Potential of Diet and Risk of Suicide Among Midlife and Older U.S. Adults

2022Postdoctoral Fellowship

Amount Awarded: $132,900

Focus Area: Psychosocial Studies

Chirag Vyas, MBBS, MPH

Chirag Vyas, MBBS, MPH

Massachusetts General Hospital

Inside the Research

Inflammation and impaired glucose metabolism are key biological pathways linked to an increased risk of suicide. Limited evidence exists to inform how diet, a modifiable lifestyle factor, reduces suicide mortality by modifying key pathways relevant to suicide risk. This study will relate inflammatory and insulinemic diet scores with subsequent risk of suicide among approximately 2,000,000 midlife and older adults. Secondarily, this study will examine the mediator role of depression in inflammatory and insulinemic diet-suicide risk associations.