Inflammatory and Insulinemic Potential of Diet and Risk of Suicide Among Midlife and Older U.S. Adults
Amount Awarded: $132,900
Focus Area: Psychosocial Studies
Chirag Vyas, MBBS, MPH
Massachusetts General Hospital
Inside the Research
Inflammation and impaired glucose metabolism are key biological pathways linked to an increased risk of suicide. Limited evidence exists to inform how diet, a modifiable lifestyle factor, reduces suicide mortality by modifying key pathways relevant to suicide risk. This study will relate inflammatory and insulinemic diet scores with subsequent risk of suicide among approximately 2,000,000 midlife and older adults. Secondarily, this study will examine the mediator role of depression in inflammatory and insulinemic diet-suicide risk associations.