MicroRNA Mediators of Early-Life Stress Vulnerability in Suicidal Behavior
2019 Distinguished Investigator Grant
Amount Awarded: $125,000
Focus Area: Genetic Studies
Yogesh Dwivedi, Ph.D.
University of Alabama at Birmingham
Early life stress has been shown to contribute to suicide risk, but the mechanisms are unknown. Genetics play a role in brain function, and alterations in expression of specific microRNAs — the parts of genes that are responsive to environmental cues — may have an effect. Understanding the relationship between microRNAs, stress, and suicide has implications for developing novel treatments and suicide prevention strategies.