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Modulation of Brain Plasticity in the Development of Suicidal Behaviors

2022Young Investigator Grant

Amount Awarded: $90,000

Focus Area: Neurobiological Studies

Corina Nagy, Ph.D.

Corina Nagy, Ph.D.

McGill University (Canada)

Inside the Research

Early developmental periods have profound effects on the organization and function of our brains, and adversity during childhood is a significant risk factor for suicide later in life. Perineural nets (PNNs) are malleable structures that impact the developing brain by stabilizing connections between cells. Changes to PNNs have been associated with suicidal behaviors, so identifying the source of PNN components and their susceptibility to childhood adversity can help us understand this relationship.