Neurophysiological Responses to Stress: A Biomarker of Risk for Suicide in Bipolar Disorder
2021 Standard Research Grant
Amount Awarded: $99,024
Focus Area: Neurobiological Studies
Elizabeth Lippard, Ph.D.
University of Michigan
Inside the Research
Brain regions that are sensitive to stress—and regulate physiological responses to stress—are implicated in suicide behavior. In bipolar disorder, greater sensitivity to stress and changes in brain regions that underlie stress response emerge over adolescence. How the brain responds to stress could contribute to risk for suicidal thoughts and behavior. This study investigates neurophysiological responses to stress as a risk factor for suicide in youth with bipolar disorder to inform suicide prevention efforts.