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Psilocybin-Assisted Therapy for Suicidal Thoughts and Behaviors in PTSD: A Pilot Study

2023 Early Career Research Grant

Amount Awarded: $107,227

Focus Area: Clinical Treatment

Amanda Tamman, Ph.D.

Amanda Tamman, Ph.D.

Baylor College of Medicine

Inside the Research

Psilocybin-assisted therapy (PAT) shows potential for addressing suicide deaths among U.S. Veterans, but requires testing in patients with low-severity suicidal thoughts to mitigate risk. The aim is to test the effect of PAT on mild suicidal thoughts and behaviors using an existing clinical trial for Veterans with PTSD, a group with high co-occurring suicide. Participants will undergo pre- and post-PAT assessments, including brain scans and social tasks associated with suicidal thoughts and PTSD to identify potential mechanisms for therapeutic effects.