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Research / Funded grants

2014 Linked Standard Research Grant

Suicidal and Self-Injurious Adolescents With Emotional Dysregulation

2 research findings from this AFSP-funded study.

Research finding · September 2026

Young people’s responses to distress may reveal information about future self-harm and suicide risk

Suicide risk assessment often relies on what people are able and willing to report about their thoughts, emotions, and recent behavior. These conversations are essential, but self-report has limitations: people may fear stigma or hospitalization, have difficulty recognizing or describing what they are experiencing, or choose not to disclose suicidal thoughts. Researchers have therefore been exploring whether behavioral tasks could complement traditional assessments by measuring psychological processes as they happen. One area of interest is how people respond to frustration and distress, including their emotional reactions and ability to persist through an uncomfortable experience. Finding objective measures associated with future suicidal behavior could eventually give clinicians another source of information alongside conversations and questionnaires, particularly for adolescents with a history of suicidal behavior or self-harm.

With their Linked Standard Research Grant, Dr. Joan Asarnow, Dr. Michele Berk, and Dr. Marsha Linehan examined whether adolescents’ responses during a computerized frustration task could help predict self-harm, suicidal ideation, and depression over the following year. The study followed 102 adolescents with histories of recurrent self-harm who completed the Mirror Tracing Persistence Task, which requires participants to trace geometric shapes under deliberately frustrating conditions while researchers measured changes in emotion and how long they persisted. While equivalent at the beginning, adolescents who showed less increase in negative emotion during the task went on to report greater self-harm, suicidal ideation, and depression severity across 12 months, while persistence and changes in positive emotion did not predict these outcomes. Although it may seem surprising that a weaker negative reaction predicted worse outcomes, the finding aligns with previous depression research suggesting that blunted emotional responses to distressing experiences may be a marker of greater depressive symptoms, which themselves often co-occur with self-harm and suicidal ideation. Although the finding requires replication and does not mean the task can currently determine an individual’s suicide risk, it suggests that measuring emotional responses as they happen may provide information about future risk for suicidal and self-harm behaviors that self-report alone cannot capture.

Citation: López R Jr, Ellis AJ, Henson V, Berk MS, McCauley E, Asarnow JR. The mirror tracing persistence task: an indicator of future adolescent suicide risk? Psychiatry Res Commun. 2026;6(3):100265. https://doi.org/10.1016/j.psycom.2026.100265

This finding comes from an AFSP-funded study — see the grant below ↓

Research finding · September 2024

Dialectical behavior therapy is a strong treatment for youth with suicidal thoughts and behaviors

Suicide is the second leading cause of death among 10- to 14-year-olds and the third leading cause of death among 15- to 24-years-olds in the United States, yet there is a limited amount of evidence-based interventions that have demonstrated efficacy in decreasing suicide attempts and nonsuicidal self-injury (NSSI) in adolescents. Dialectical behavior therapy (DBT) is a talk therapy grounded in mindfulness and behavior therapy that includes teaching skills to manage intense emotions, cope with challenging situations, and improve relationships. Previous research has shown that DBT can be effective in reducing risk for suicide attempt and NSSI, but more studies are needed to inform optimal treatment approaches.

Drs. Michele Berk, Joan Asarnow, and Marsha Linehan conducted a randomized, controlled trial with 173 adolescents aged 12-18 years old with repetitive self-harm (including at least one prior suicide attempt) and elevated suicidal ideation. Each adolescent received six months of DBT or individual and group supportive therapy (IGST) and were followed up with for six months following treatment. The team found that over 70% of adolescents reported remission of suicide attempts after receiving either treatment. For adolescents who received DBT rather than IGST, there were significantly higher rates of remission and recovery, and lower rates of relapse and recurrence for suicide attempts. While DBT was more effective for stopping suicidal behavior, both therapies had similar effects on non-suicidal self-injury (NSSI), though DBT showed better long-term results.

Citation: Berk, M. S., Gallop, R., Asarnow, J. R., Adrian, M. C., Hughes, J. L., & McCauley, E. (2024). Remission, Recovery, Relapse, and Recurrence Rates for Suicide Attempts and Nonsuicidal Self-Injury for Suicidal Youth Treated With Dialectical Behavior Therapy or Supportive Therapy. Journal of the American Academy of Child & Adolescent Psychiatry. https://doi.org/10.1016/j.jaac.2024.01.012

This finding comes from an AFSP-funded study — see the grant below ↓

The grant behind this work · 2014 Linked Standard Research Grant

Suicidal and Self-Injurious Adolescents With Emotional Dysregulation

Michele Berk, Ph.D.

Michele Berk, Ph.D.

Harbor-UCLA Medical Center

Marsha Linehan, PhD

Marsha Linehan, Ph.D.

University of Washington

Joan Asarnow, PhD

Joan Asarnow, Ph.D.

University of California, Los Angeles

Amount awarded
$214,000
Focus area
Psychosocial

Inside the Research

Bios: Dr. Asarnow received her Ph.D. in psychology from the University of Waterloo (Ontario) in 1980. She is currently Professor of Psychiatry and Biobehavioral Sciences at UCLA.

Dr. Linehan received her Ph.D in social psychology from Loyola University in 1971. She is currently Professor of Psychology and Adjunct Professor in Psychiatry and Behavioral Sciences at the University of Washington.

Dr. Berk received her Ph.D in clinical psychology from New York University in 2001. She is currently Associate Clinical Professor, Department of Psychiatry and Biobehavioral Sciences, at the David Geffen School of Medicine of UCLA.

Grant Category: Community intervention studies

Abstract: Suicide is the second leading cause of death among adolescents. Adolescents are also at a high risk for insomnia and sleep problems which lead to self-harm and suicidal thoughts. Adolescents who die by suicide are five times more likely to have insomnia during the week before death. Dr. Asarnow, Dr. Linehan, and Dr. Berk’s study will focus on clarifying the significance of ongoing sleep problems in relation to self-harm and suicide. Sleep problems are also related to difficulties regulating emotion which is a pathway to self-harm behaviors. Their study will build upon an existing NIMH-funded study, and they will examine sleep from self-report measurements. They will use a laboratory measure to assess processes that affect emotion regulation. There will be 100 youth participants aged 12-18 who are at high risk of suicide attempts due to their suicidal ideation, emotion dysregulation, and repetitive self-harm. Youth will be asked to record their sleep habits for 10 days and they will also participate in a telephone interview about their suicidal ideation and self-harm. The parents of the youth will also participate in the phone interview. These follow up measures will be assessed at 6 months and 12 months.

Impact: Improved suicide risk detection and interventions for suicidal adolescents with significant insomnia.

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