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Research / Funded grants

2020 Young Investigator

Suicidal behavior in elementary school-aged youth: Assessment of familial factors and neurocognitive functioning

2 research findings from this AFSP-funded study.

Research finding · February 2024

Some characteristics in school-aged children contribute to suicidal thoughts and behaviors

Though infrequent when compared to other age groups, suicidal thoughts and behaviors (STBs) have increased in elementary school-aged children in recent years. Despite prior research indicating that feelings of hopelessness, mood disorder symptoms, and a familial history of suicidal behaviors may be associated with STBs in preteens, little is known in terms of established risk factors (or contributors to risk). More research has been needed to improve screening, assessment, and prevention efforts for this age group.

To help determine risk factors for STBs in preteens, Dr. Arielle Sheftall examined the neurocognitive (skills linked to specific parts of the brain) and clinical characteristics of 93 elementary school-aged children with and without a history of STBs. After administering a series of clinical interviews and neurocognitive tests, Dr. Sheftall found that children who reported a history of suicidal thoughts and behaviors were typically older, had higher levels of depressive and anxiety symptoms, and were more likely to have a parent with a history of STBs. Poorer performance in neurocognitive skills, such as attentional flexibility and inhibitory control were also significantly associated with STBs. These results provide targets for future suicide prevention efforts in elementary-aged children and offer the opportunity for upstream interventions before STBs develop.

Citation: Chen, Q., Armstrong, S. E., Vakil, F., Bridge, J. A., Keilp, J. G., & Sheftall, A. H. (2023). Neurocognitive and clinical characteristics of elementary school-aged children with a history of suicidal thoughts and behaviors. Journal of Affective Disorders, 339, 318–324. https://doi.org/10.1016/j.jad.2023.07.038

This finding comes from an AFSP-funded study — see the grant below ↓

Research finding · November 2023

Certain personal factors in adolescents aligned with distinct patterns in suicidal thoughts and behaviors

Suicidal thoughts, plans, and attempts manifest in several distinct ways within adolescents. Some adolescents may only have suicidal thoughts, while never making a plan or attempt. Others may have suicidal thoughts and a plan, but never make an attempt. Suicide attempts may occur in some adolescents who had suicidal thoughts and a plan, and others who had neither. It’s important to research these distinct patterns to understand more about the factors that could be associated with each. Knowledge about these factors could help clinicians while screening adolescents for risk of suicidal behaviors and provide cues for intervention.

In her research, Dr. Arielle Sheftall examined the demographic, psychological, social, and substance use factors associated with past-year suicidal thoughts, plans, and attempts from 7,491 high school-aged adolescents. Dr. Sheftall found that 24% of the adolescents had suicidal thoughts only in the past year, 38% had suicidal thoughts and a plan and did not attempt suicide, 35% attempted suicide after having thoughts and a plan, and 3% made a suicide attempt with no previous thoughts or plans. She also found that all substance use and psychosocial factors (e.g., being bullied at school or online, feeling sad or hopeless, and having a history of sexual violence victimization) were associated more with adolescents who attempted suicide. The groups that were most likely to have no suicidal thoughts or plans before an attempt were male or Black. Since the goal of this study was to identify patterns, the next step will be to understand the differences between them to inform suicide prevention screening.

Citation: Romanelli, M., Sheftall, A. H., Irsheid, S. B., Lindsey, M. A., & Grogan, T. M. (2022). Factors Associated with Distinct Patterns of Suicidal Thoughts, Suicide Plans, and Suicide Attempts Among US Adolescents. Prevention Science, 23(1), 73-84, http://dx.doi.org/10.1007/s11121-021-01295-8

This finding comes from an AFSP-funded study — see the grant below ↓

The grant behind this work · 2020 Young Investigator

Suicidal behavior in elementary school-aged youth: Assessment of familial factors and neurocognitive functioning

Arielle Sheftall, Ph.D.

Arielle Sheftall, Ph.D.

The Abigail Wexner Research Institute at Nationwide Children's Hospital

Mentor: Jeffrey Bridge, Ph.D., The Abigail Wexner Research Institute at Nationwide Children's Hospital

Amount awarded
$90,000
Focus area
Psychosocial

Inside the Research

Research suggests that suicide risk factors differ between younger children who die by suicide compared to older youth. This study will examine neurocognitive (brain) functioning and factors associated with family behaviors and relationships in children ages 6 to 11 years, with and without a history of suicidal behavior. An understanding of the risk factors for suicidal behavior in childhood can be used to inform relevant child-specific suicide prevention and intervention programs.

Full scientific abstract

Suicide is the 9th leading cause of death in children under 12 years old. Research has suggested risk factors may differ in elementary school-aged children who die by suicide compared to older youth. To date, little research has investigated risk factors in children with suicidal behavior (SB) to confer which factors may be relevant for prevention and intervention efforts. The proposed study intends to fill these gaps in the literature by examining risk factors in children, 6-11 years, with (SB+) and without a history of suicidal (SB-). Within the SB+ group, children with suicidal ideation only (SI+) and children with a history of suicide attempt (SA+) will be recruited. The specific aims and hypotheses are: Aim 1: Examine the association between neurocognitive functioning and SB in elementary school-aged children. Hypothesis 1a: SA+ group will exhibit more neurocognitive deficits compared to the SI+ and SB- groups and the SI+ group will display more neurocognitive deficits compared to SB- group but less than the SA+ group (SA+ > SI+ > SB-). Hypothesis 1b: Parental/caregiver neurocognitive deficits will be positively correlated with child neurocognitive deficits. Aim 2: Investigate the association between familial factors and SB in elementary school-aged children. Hypothesis: SA+ group will have less reported familial cohesion/adaptability, poorer reported parenting behaviors, insecure attachment styles, and express negative social communication/interactions compared to the SI+ and SB- groups. SI+ group will have less reported familial positive attributes (e.g., positive parenting behaviors) when compared to the SB- group (SA+ < SI+ < SB-). Exploratory Aim: Investigate the potential main and moderating effects of ADHD symptomatology on SB in elementary school-aged children. We will also collect information on key risk and protective factors to examine the independent and interactive effects of neurocognitive functioning and familial factors on SB. Measures will include interview questions concerning SB of the child, parent/caregiver, and 1st/2nd degree relatives, interview questions to evaluate motivations of SB in children, computer tasks assessing neurocognitive functioning in both the child and parent/caregiver, computerized measures assessing peer relationship quality, an observational task to evaluate familial interaction and parent/caregiver/child communication, and questionnaires to assess risk factors associated with SB (e.g., depression). The proposed project is in line with AFSP's strategic goals to accelerate progress in the field of suicide research and to reach individuals at risk for suicide and suicidal behavior in order to save lives. Successful completion of this project will contribute to the discovery of specific risk factors associated with SB in elementary school-aged children and provide information to assist with the creation of developmentally appropriate intervention programming for youth at-risk. This proposed study will set the foundation for future research to follow this at-risk group into late childhood/early adolescence to determine which factors are predictive of future SB in youth who experience SB in early childhood.

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