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Research / Funded grants

2023 Standard Research Grant

Suicidal Ideation and Attempts among Youth with Physical-Mental Comorbidity: A Pan-Canadian Study

1 research finding from this AFSP-funded study.

Research finding · February 2026

Chronic health conditions and mental health challenges affect suicide risk in adolescents

Living with a chronic health condition during adolescence can place significant demands on a young person’s emotional, social, and physical well-being. Managing symptoms, attending medical appointments, navigating school demands, and trying to maintain friendships can place a steady strain on emotional well-being. When these conditions co-occur with mental or neurodevelopmental disorders (i.e., a pattern known as multimorbidity) those strains can deepen. Youth with multimorbidity often navigate complex care systems, ongoing symptoms, disruptions to school and peer life, and heightened stress within their families. While prior research has shown that both physical illness and mental health conditions independently increase suicide risk, far less is known about how suicidal thoughts and behaviors show up among adolescents living with both. It also remains unclear which individual, family, and social factors further shape risk within this particularly vulnerable group.

To explore this question, Dr. Mark Ferro used his AFSP-funded grant to examine data from 3,535 Canadian youth aged 15 to 17 who participated in the nationally representative 2019 Canadian Health Survey on Children and Youth. Of these adolescents, 1,041 reported multimorbidity, defined as having at least one chronic physical illness alongside a mental or neurodevelopmental disorder. Nearly half of youth with multimorbidity reported recent feelings of hopelessness, more than one in four reported suicidal thoughts, and almost one in five reported having attempted suicide in the past year, rates far higher than those seen among youth without chronic physical conditions. Certain experiences were linked to greater risk for suicidal thoughts and behavior, including being female, experiencing bullying or other forms of victimization, having a parent or guardian with poor mental health, and identifying as having a non-heterosexual sexual orientation. The results are consistent with a cumulative burden shaped by health challenges, social stress, and family context. Dr. Ferro highlighted the need for integrated, family-centered care that brings physical and mental health services together, along with early screening and supportive, affirming environments that can help reduce risk for youth managing multiple and intersecting challenges.

Citation: Fearon, D., Luther, A., Dubin, J. A., Duncan, L., Browne, D., Colman, I., & Ferro, M. A. (2025). Factors associated with suicidality among youth in Canada with co-occurring physical illness and mental/neurodevelopmental disorders. Psychiatry research, 354, 116785. https://doi.org/10.1016/j.psychres.2025.116785

This finding comes from an AFSP-funded study — see the grant below ↓

The grant behind this work · 2023 Standard Research Grant

Suicidal Ideation and Attempts among Youth with Physical-Mental Comorbidity: A Pan-Canadian Study

Mark A. Ferro, PhD

Mark A. Ferro, Ph.D.

University of Waterloo (Canada)

Amount awarded
$124,499
Focus area
Psychosocial

Inside the Research

Although having a chronic physical illness (e.g., diabetes) increases risk for suicidal ideation and behavior among youth, little is known about suicide burden amongst individuals with co-occurring physical and mental illness. This project aims to understand factors associated with suicidal ideation and behavior in youth with physical-mental comorbidity by studying participants in the Canadian Health Survey of Children and Youth. Findings will inform intervention planning to reduce suicidal ideation and behavior in this vulnerable population.

Full scientific abstract

AIMS/HYPOTHESES: This project uses epidemiological data from the 2019 Canadian Health Survey of Children and Youth (CHSCY) to study the intersection of physical illness, mental or neurodevelopmental disorder (MND), and suicide ideation and attempts (suicidality) in youth. Specifically, to 1–estimate prevalence of suicidality among youth with physical-MND comorbidity (H1: youth with physical-MND comorbidity will have the highest prevalence of suicidality compared to physical illness only, MND only, healthy); 2–quantify magnitudes of association between physical-MND comorbidity and suicidality, adjusting for sociodemographic/economic factors (H2: associations will remain robust after adjustment); 3–identify multilevel correlates (individual, family, neighborhood) of suicidality among youth with physical-MND comorbidity (H3: correlates of suicidality will include age, sex, transgender identity, disability, parent psychopathology, strained relationships, lower income, and neighbourhood disadvantage); 4–contrast patterns of psychiatric services use among youth with physical-MND comorbidity who have vs. have not experienced suicidality (H4: youth who experienced suicidality will have used more services and report more barriers); and, 5—test whether physical-MND comorbidity moderates associations between suicidality and health outcomes (H5: suicidality will be associated with poorer psychosocial and academic achievement and increased use of substances; effects will be larger for youth with physical-MND comorbidity).

 

METHODS: Conducted by Statistics Canada, the CHSCY collected data from 92,170 children (1-17 years) and their primary-caregiving parent, providing a large, representative sample of Canadian youth. Measures of child physical illness (e.g., asthma, diabetes, epilepsy), mental illness (e.g., anxiety, mood, eating disorders), and neurodevelopmental disorders (e.g., ADHD, autism), family environment, and sociodemographics are available using youth and parent informants. Neighborhood characteristics and psychiatric services use are available via linkage with Canadian Census and national administrative health data (e.g., consults, emergency department visits, hospitalizations). Questions about suicidality were restricted in the CHSCY to youth 15-17 years (n=15,670), which forms the analytic sample. Youth were asked, “In the past 12 months, did you ever seriously consider attempting suicide or taking your own life?” and “Have you ever attempted suicide or tried taking your own life?”. Regression-based analyses will account for the complex design of the CHSCY and best practices to understand sex-/gender-based effects will be applied across all models tested.

 

IMPACT/NEXT STEPS: Findings will provide estimates of suicidality among youth with physical-MND comorbidity, which will inform intervention planning to prevent suicidality in this understudied, but vulnerable population. Modelling correlates of suicidality will advance understanding of the relative and joint effects of factors at multiple levels—information needed to target prevention efforts. Understanding patterns of psychiatric service use among youth with physical-MND comorbidity who experienced suicidality is vital to understanding barriers to services access. This will inform whether use matches need, identifying opportunities to advise providers and policy makers about upstream resources to prevent suicidality. The CHSCY was recently funded for a longitudinal follow-up. When these data become available, targets for intervention identified in this study will be investigated (in future work) to examine the extent to which incidence of suicidality in youth with physical-MND comorbidity is reduced. This evidence is needed to support advocacy for resource allocation.

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