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Understanding Suicide through Postmortem Targeted Brain Multi-omics

2021 Young Investigator Grant
Amount Awarded: $90,000
Focus Area: Genetic Studies

Matthew Girgenti, Ph.D.

Matthew Girgenti, Ph.D.
Yale School of Medicine

Mentor: John Krystal, M.D.

Inside the Research

The majority of epidemiologic studies have shown PTSD is associated with an increased risk of suicide. However, the molecular determinants of both traits are not well understood and predictive biomarker discovery as well as therapeutic development in this area is still in its infancy. The goal of this project is to elucidate the molecular determinants that contribute to the development of PTSD and suicidal behavior using single cell genomics in postmortem brain tissue.